4.9 - Star Rated By
Operators
EPA-Designated
Minimum Risk

vs. Rat poison

Poison kills the rats that eat it. It doesn't stop the ones that come next.

Poison does its job. The problem is what happens four to six weeks after the colony clears. Empty territory in a food-rich urban block fills from the surrounding population — at full breeding rate — before your next scheduled treatment.

Where it works

It kills what's there. That part works.

Rodent poison placed along travel paths and near entry points will kill the rats that eat it. The colony that's currently active goes down. For light infestations or one-off incidents, it's often the right first tool.

The problem isn't what it does. The problem is what happens four to six weeks after it does it.

Where it falls short

Killing the colony makes the territory available.

Rats are territorial. When a colony is present, their scent markers keep other groups out. Remove that colony with poison and those marks fade within days. The food source didn't move. The building didn't move. Rats from the surrounding block detect the open territory and fill it within weeks.

The replacement colony comes in at full reproduction rate. You're back to baseline before the next scheduled visit.

Other problems with rodent poison

The cycle isn't the only issue.

Secondary kill risk

Hawks, owls, and foxes that eat poisoned rats absorb the toxicant. The strongest anticoagulant rodenticides carry the highest secondary risk and have been under increasing EPA restrictions for consumer use.

NYC restrictions

In 2021, NYC restricted commercial use of the strongest class of anticoagulant rodenticide. What was standard practice a few years ago is no longer on the approved list, and the list keeps changing.

It produces dead rats

Poison creates visible evidence — dead rodents in food storage, near prep surfaces, or where tenants find them. For restaurants, that's its own inspection and liability exposure even when the treatment is technically working.

How they compare

Poison and fertility management solve different parts of the problem.

 Rat poisonFertility management ( Evolve)
Kills the current colonyYesPhase 1 of the program handles this with your existing vendor
Reduces reproduction rate over timeNoYes — that's the mechanism
Stops the replacement colony from formingNoReduces the rate at which it forms
Secondary kill riskYes — anticoagulants in particularNo — EPA-designated minimum risk
Safe for continuous food-environment useRestrictedYes
90-day declining trend documentationNoMonthly track count plates and written report

The 90-day program uses both. Phase 1 clears the current colony with whatever treatment is already in place. Phase 2 adds Evolve on top to prevent the replacement from forming at the same rate. Together they produce a declining trend. Separately, neither does.

Field data

Numbers from monitored urban deployments.

What a combined program produces over 90 days.

79%
reduction in rodent track presence
Location A — 5-month urban field study, Aug 2025 to Jan 2026
88%
drop in track density at the same site
Tracks per monitoring plate declined even where rodents were still present
90%
fertility reduction potential
When Evolve runs alongside an active pest control program

Source: SenesTech, Inc. — February 18, 2026

More comparisons

See the layer next to the other tools you already use.

Keep the poison. Add the layer that stops the cycle.

The program works with whatever treatment is already running. Your vendor stays. We add the fertility layer on top.

  • Layered onto your existing pest program
  • EPA-designated minimum-risk bait
  • Documented monthly reporting
  • Month-to-month, no long contracts